Getting rid of nested backpacks fixed me. I've logged close to 100 hours playing this game, and run into all sorts of shitty bugs haha. Most frustrating ones are the wipes, but meh. This was a new one for me this morning. Server list populates, I pick one out, load in, see my character appear all the good stuff but can't equip my weapon, open doors, anything (I've run into a similar bug where this happens, I mash my mouse and keyboard then try to equip and it works). I see stuff on the ground, can't pick it up. Reload a new server. Same thing, try like 4 times, right clicking items it just spins on the "retrieving" message. Reinstall the game, check my ports, going crazy. Then I look in my inventory and notice that some of the things I was trying to pick up are in my inventory. So test time, I tried to pick one thing up and drop something already in my inventory, switched servers and success. So then I start thinking what is different and the only thing is that this morning I started making "starter" packs for buddies with a hunter pack, can opener, some other misc stuffs, then stacking that bag in a bag. I had 4-5 of the things. So I log into a server, drop all the bags including the one on my back, reload the same server and magically I can interact with stuff again, I then spend 20 minutes unpacking all the bags and cursing life but back to normal play here. Hope this helps someone!